I use Party Shuffle at work, pulling songs in from a SPL, with cross-fades turned on. Sometimes when I hear a song, especially one of my all-time favorites, I don't want another song to come immediately after it. I just want silence to let the tune bounce around my head for a bit. Or it's the last song of the day on a Friday afternoon, and I don't want a slow/quiet song to come on after it and ruin my mood.
So instead of trying to time the press of the stop button, I made a normal playlist called "Silence" which contains no songs, and change my Party Shuffle source to that. That clears out any songs after the currently playing one which you can't otherwise do (if you delete one it's replaced).